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Дилан Томас (1914–1953) — английский поэт.
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Вероятно, отсылка к мультфильму Moby Dick and the Mighty Mightor (1967–1969). Главный герой мультфильма — пещерный человек Тор, у которого есть прирученный динозавр Тог. Однажды персонажам удается спасти пожилого отшельника, и он в знак благодарности передает им дубинку, обладающую волшебными свойствами. С ее помощью Тор становится необычайно сильным и смелым, обретая при этом новое имя Майтор (Mightor — от англ. might, то есть «мощь», «сила»), а Тог превращается в огнедышащего дракона. С этого момента они вместе решают посвятить себя неустанной борьбе со злом.
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Фрэнсис Бэкон (1561–1626) — английский философ, политический деятель, писатель.
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Парацельс (1493–1541) — врач, философ эпохи Возрождения.
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Тихо Браге (1546–1601) — датский астроном эпохи Возрождения.
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Роберт Бойль (1627–1691) — английский химик и физик.
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Эспри Д. Биохакинг мозга. Проверенный план прокачки вашего мозга за две недели. М.: Манн, Иванов и Фербер, 2017. Прим. ред.
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Органелла, или органоид, — структура, которая находится внутри клетки и выполняет определенную функцию.
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E. Giovannucci et al. Diabetes and Cancer: A Consensus Report. — Diabetes Care 33. № 7 (2010): 1674–1685. https://doi.org/10.2337/dc10-0666.
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Ch. Holscher. Diabetes as a Risk Factor for Alzheimer’s Disease: Insulin Signalling Impairment in the Brain as an Alternative Model of Alzheimer’s Disease. — Biochemical Society Transactions 39. № 4 (August 2011): 891–897. https://doi.org/10.1042/BST0390891.
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Kr. Bhaskaran et al. Body-Mass Index and Risk of 22 Specific Cancers: A Population-Based Cohort Study of 5·24 Million UK Adults. — The Lancet 384. № 9945 (August 30, 2014): 755–765; K. Brown et al. The Fraction of Cancer Attributable to Modifiable Risk Factors in England. — Wales, Scotland, Northern Ireland, and the United Kingdom in 2015. — British Journal of Cancer 118. № 8 (April 2018): 1130–1141.
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Ch. J. Murray, M. Ng, A. Mokdad. The Vast Majority of American Adults Are Overweight or Obese, and Weight Is a Growing Problem Among US Children. — Institute for Health Metrics and Evaluation (IHME). May 28, 2014. http://www.healthdata.org/news-release/vast-majority-american-adults-are-overweight-or-obese-and-weight-growing-problem-among.
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Тиреоидные гормоны вырабатываются щитовидной железой.
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Inflammatory Hypothesis Confirmed: Reducing Inflammation Without Lowering Cholesterol Cuts Risk of Cardiovascular Events. Health Canal. August 27, 2017. https://www.healthcanal.com/blood-heart-circulation/heart-disease/240113-inflammatory-hypothesis-confirmed-reducing-inflammation-without-lowering-cholesterol-cuts-risk-cardiovascular-events.html.
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University of Colorado at Boulder. Fountain of Youth for Heart Health May Lie in the Gut: Age-Related Changes to Microbiome Fuel Vascular Decline. New Study Shows. ScienceDaily, March 19, 2019. www.sciencedaily.com/releases/2019/03/190319163527.htm.
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R. Nemati et al. Deposition and Hydrolysis of Serine Dipeptide Lipids of Bacteroidetes Bacteria in Human Arteries: Relationship to Atherosclerosis. — Journal of Lipid Research 58 (October 2017): 1999–2007. https://doi.org/10.1194/jlr.M077792.
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Th. Meyer et al. Attention Deficit-Hyperactivity Disorder Is Associated with Reduced Blood Pressure and Serum Vitamin D Levels: Results from the Nationwide German Health Interview and Examination Study for Children and Adolescents. — European Child & Adolescent Psychiatry, 26. № 2 (February 2017): 165–175. https://doi.org/10.1007/s00787-016-0852-3.
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K. McKeever. Asperger Syndrome Tied to Low Cortisol Levels. — HealthDay, April 2, 2009. https://consumer.healthday.com/cognitive-health-information-26/autism-news-51/asperger-syndrome-tied-to-low-cortisol-levels-625706.html.
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M. Donath, St. Shoelson. Type 2 Diabetes as an Inflammatory Disease. — Nature Reviews Immunology 11. № 2 (February 2011): 98–107. https://doi.org/10.1038/nri2925.
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University of California — San Diego. Type 2 Diabetes: Inflammation, Not Obesity, Cause of Insulin Resistance. — ScienceDaily, November 7, 2007. https://www.sciencedaily.com/releases/2007/11/071106133106.htm.
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Skinny fat — с английского можно перевести как «худой, но жирный».
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Y. Wang et al. Association of Muscular Strength and Incidence of Type 2 Diabetes. — Mayo Clinic Proceedings 94. № 4 (April 2019): 643–651. https://doi.org/10.1016/j.mayocp.2018.08.037.
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S. Weimer et al. D-Glucosamine Supplementation Extends Life Span of Nematodes and of Ageing Mice. — Nature Communications 5. April 8, 2014: 3563. https://doi.org/10.1038/ncomms4563.
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R. Weindruch, R. Sohal. Seminars in Medicine of the Beth Israel Deaconess Medical Center. Caloric Intake and Aging. — New England Journal of Medicine 337. № 14 (October 2, 1997): 986–994. https://doi.org/10.1056/NEJM199710023371407.
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D-Glucosamine as an Example of Calorie Restriction Mimetic Research. — Fight Aging! April 8, 2014. https://www.fightaging.org/archives/2014/04/d-glucosamine-as-an-example-of-calorie-restriction-mimetic-research/.
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Karen W. Della Corte et al. Effect of Dietary Sugar Intake on Biomarkers of Subclinical Inflammation: A Systematic Review and Meta-Analysis of Intervention Studies. — Nutrients 10. № 5 (2018): 606. https://doi.org/10.3390/nu10050606.
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S. Singh. Post-Prandial Hyperglycemia. — Indian Journal of Endocrinology and Metabolism 16. № 8 (December 2012): 245–247. https://doi.org/10.4103/2230–8210.104051.
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Зональная диета — методика снижения веса, разработанная американским диетологом Барри Сирсом в 1996 году. Заключается в разделении белков, углеводов и жиров на блоки (зоны). Прим. ред.
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Криптонит — в комиксах издательства DC Comics единственное из всех веществ, способное нанести вред Супермену.
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Провоспалительный — способствующий развитию воспалительной реакции.
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Federation of American Societies for Experimental Biology, Scientists Remove Amyloid Plaques from Brains of Live Animals with Alzheimer’s Disease. — ScienceDaily. www.sciencedaily.com/releases/2009/10/091015091602.htm (accessed July 16, 2019).
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ОФЭКТ, или ОЭКТ, — однофотонная эмиссионная компьютерная томография (англ. Single-photon emission computed tomography, SPECT) — диагностический метод создания томографических изображений распределения радионуклидов. Прим. ред.
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41 Percent of Americans Will Get Cancer. — UPI Health News, May 6, 2010. https://www.upi.com/41-percent-of-Americans-will-get-cancer/75711273192042/.
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L. Coussens, Z. Werb. Inflammation and Cancer. — Nature 420. № 6917 (2002): 860–867. https://doi.org/10.1038/nature01322.
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Раньше рудокопы брали с собой в шахту клетку с канарейкой, поскольку эта птица очень чувствительна к малейшему количеству газов в воздухе. Когда канарейка начинала вести себя необычно, угольщики уходили с этого участка.
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Функциональная геномика — научное направление, целью которого является изучение генов, кодирующих белки или влияющих на их функционирование, а также исследование роли этих белков в биохимических процессах всего организма. Может также включать исследования естественных генетических вариаций во времени (например, развитие организма) или пространстве (например, частей тела), а также функциональные нарушения, такие как мутации. Прим. ред.
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Функциональная медицина подразумевает комплексный подход к лечению: разработку стратегии профилактики болезней, выявления и устранения факторов риска и первопричин развития заболеваний, восстановления здоровья и увеличения продолжительности жизни. Объектом терапии служит не болезнь, а состояние организма в целом; основное внимание специалистов направлено на оптимизацию всех органов и систем человека. Автор термина — американский биохимик Джеффи Бленд, специализирующийся на вопросах питания. С начала 1990-х годов эта система лечения завоевала мировую популярность, несмотря на критическое отношение к ней некоторых представителей клинической медицины. Тем не менее следует отметить, что большинство данных, приведенных в книге, подкреплено результатами научных исследований. Прим. ред.
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H. Karakelides, K. Nair. Sarcopenia of Aging and Its Metabolic Impact. — Current Topics in Developmental Biology 68 (2005): 123–148. https://doi.org/10.1016/S0070-2153(05)68005-2.
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E. Volpi, R. Nazemi, S. Fujita. Muscle Tissue Changes with Aging. — Current Opinion in Clinical Nutrition and Metabolic Care 7. № 4 (2004): 405–410. https://doi.org/10.1097/01.mco.0000134362.76653.b2.
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J. Golomb et al. Hippocampal Atrophy in Normal Aging. An Association with Recent Memory Impairment. — Archives of Neurology 50. № 9 (September 1993): 967–973. https://doi.org/10.1001/archneur.1993.00540090066012.
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M. Stimpfel, N. Jancar, I. Virant-Klun. New Challenge: Mitochondrial Epigenetics? — Stem Cell Reviews and Reports 14. № 1 (February 2018): 13–26. https://doi.org/10.1007/s12015-017-9771-z.
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J. Kirkland, T. Tchkonia. Cellular Senescence: A Translational Perspective. — EBioMedicine 21 (July 2017): 21–28. https://doi.org/10.1016/j.ebiom.2017.04.013.
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V. Korolchuk et al. Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link? — EBioMedicine 21 (July 2017): 7–13. https://doi.org/10.1016/j.ebiom.2017.03.020.
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O. Jeon et al. Senescent Cells and Osteoarthritis: A Painful Connection. — Journal of Clinical Investigation 128. № 4 (April 2, 2018): 1229–1237. https://doi.org/10.1172/JCI95147.
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D. Huffman, M. Schafer, N. LeBrasseur. Energetic Interventions for Healthspan and Resiliency with Aging. — Experimental Gerontology 86 (December 15, 2016): 73–83. https://doi.org/10.1016/j.exger.2016.05.012.
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Ch. Bannister et al. Can People with Type 2 Diabetes Live Longer Than Those Without? A Comparison of Mortality in People Initiated with Metformin or Sulphonylurea Monotherapy and Matched. — Non-Diabetic Controls, Diabetes, Obesity and Metabolism 16. № 11 (November 2014): 1165–1173. https://doi.org/10.1111/dom.12354.
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Agn. Śmieszek et al. Antioxidant and Anti-Senescence Effect of Metformin on Mouse Olfactory Ensheathing Cells (mOECs) May Be Associated with Increased Brain-Derived Neurotrophic Factor Levels — An Ex Vivo Study. — International Journal of Molecular Sciences 18. № 4 (2017): 872. https://doi.org/10.3390/ijms18040872.
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R. Wang et al. Rapamycin Inhibits the Secretory Phenotype of Senescent Cells by a Nrf2-Independent Mechanism. — Aging Cell 16. № 3 (June 2017): 564–574. https://doi.org/10.1111/acel.12587.
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Animal Data Shows Fisetin to Be a Surprisingly Effective Senolytic. — Fight Aging! October 3, 2018. https://www.fightaging.org/archives/2018/10/animal-data-shows-fisetin-to-be-a-surprisingly-effective-senolytic/.
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P. Maher. How Fisetin Reduces the Impact of Age and Disease on CNS Function. — Frontiers in Bioscience (Scholar Edition) 7 (June 1, 2015): 58–82. https://www.ncbi.nlm.nih.gov/pubmed/25961687.
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K. Gander. Secret of Longevity Could Be Found in Traditional Japanese Plant that Appears to Slow Aging. — Newsweek, February 20, 2019. https://www.newsweek.com/anti-aging-longevity-japanese-plant-1336734.
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Uncovering the Senolytic Mechanism of Piperlongumine. — Fight Aging! May 21, 2018. https://www.fightaging.org/archives/2018/05/uncovering-the-senolytic-mechanism-of-piperlongumine/.
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Y.-J. Chen et al. Piperlongumine Inhibits Cancer Stem Cell Properties and Regulates Multiple Malignant Phenotypes in Oral Cancer. — Oncology Letters 15. № 2 (February 2018): 1789–1798. https://doi.org/10.3892/ol.2017.7486.
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F. de Lima Moreira et al. Metabolic Profile and Safety of Piperlongumine. — Nature Scientific Reports 6 (September 29, 2016): article № 33646. https://www.nature.com/articles/srep33646.
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Слово age с английского переводится как «возраст», «стареть».
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A. Gaby. Adverse Effects of Dietary Fructose. — Alternative Medicine Review 10. № 4 (December 2005): 294–306. http://www.ncbi.nlm.nih.gov/pubmed/16366738.
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M. Streeter et al. Identification of Glucosepane Cross-Link Breaking Enzymes. — Diabetes 67. № S1 (July 2018): 1229-P. https://doi.org/10.2337/db18-1229-P.
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X. Wang et al. Insulin Deficiency Exacerbates Cerebral Amyloidosis and Behavioral Deficits in an Alzheimer Transgenic Mouse Model. — Molecular Neurodegeneration 5 (2010): 46. https://doi.org/10.1186/1750-1326-5-46.
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Кетоз — состояние, при котором тело перестает получать энергию от углеводов и печень начинает преобразовывать жировые запасы тела в кетоны, то есть химические соединения, используемые организмом в качестве источника энергии.
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Цепь аминокислот, из которых состоит белок, представляет собой определенную трехмерную структуру. Формирование такой структуры называется сворачиванием белка. Иногда этот процесс протекает со сбоями, и белок сворачивается неправильно.
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J. Lite. Vitamin D Deficiency Soars in the U.S., Study Says. — Scientific American, March 23, 2009. https://www.scientificamerican.com/article/vitamin-d-deficiency-united-states/.
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Society for Neuroscience, Staving Off Alzheimer’s Disease with the Right Diet, Prescriptions. — ScienceDaily, November 13, 2007. https://www.sciencedaily.com/releases/2007/11/071107211036.htm.
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G. Notarachille et al. Heavy Metals Toxicity: Effect of Cadmium Ions on Amyloid Beta Protein 1-42. Possible Implications for Alzheimer’s Disease. — Biometals 27. № 2 (April 2014): 371–388. https://doi.org/10.1007/s10534-014-9719-6.
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P. Tchounwou et al. Heavy Metal Toxicity and the Environment, in Molecular, Clinical and Environmental Toxicology. — Experientia Supplementum, vol. 101, ed. Andrea Luch (Basel, CH: Springer, 2012): 133–164.
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E. Belyaeva et al. Mitochondria as an Important Target in Heavy Metal Toxicity in Rat Hepatoma AS-30D Cells. — Toxicology and Applied Pharmacology 231. № 1 (August 15, 2008): 34–42. https://doi.org/10.1016/j.taap.2008.03.017.
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V. Singh et al. Advanced Glycation End Products and Diabetic Complications. — The Korean Journal of Physiology & Pharmacology 18. № 1 (2014): 1–14. https://doi.org/10.4196/kjpp.2014.18.1.1.
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D. Turner. Advanced Glycation End-Products: A Biological Consequence of Lifestyle Contributing to Cancer Disparity. — Cancer Research 75. № 10 (May 2015): 1925–1929. https://doi.org/10.1158/0008–5472.CAN-15-0169.
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M. Peppa, S. Raptis. Advanced Glycation End Products and Cardiovascular Disease. — Current Diabetes Reviews 4. № 2 (May 2008): 92–100. https://www.ncbi.nlm.nih.gov/pubmed/18473756.
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N. Sasaki et al. Advanced Glycation End Products in Alzheimer’s Disease and Other Neurodegenerative Diseases. — American Journal of Pathology 153. № 4 (October 1998): 1149–1155. https://doi.org/10.1016/S0002-9440(10)65659-3.
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The BMJ, Fried Food Linked to Heightened Risk of Early Death Among Older US Women: Fried Chicken and Fried Fish in Particular Seem to Be Associated with Higher Risk of Death. — ScienceDaily, January 23, 2019. https://www.sciencedaily.com/releases/2019/01/190123191637.htm.
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Теломеры — концевые участки хромосом. Характеризуются отсутствием способности к соединению с другими хромосомами или их фрагментами и выполняют защитную функцию. Прим. ред.
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Hayflick Limit, ScienceDirect. https://www.sciencedirect.com/topics/medicine-and-dentistry/hayflick-limit.
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P. van der Harst et al. Telomere Length of Circulating Leukocytes Is Decreased in Patients with Chronic Heart Failure. — Journal of the American College of Cardiology 49. № 13 (April 3, 2007): 1459–64. https://doi.org/10.1016/j.jacc.2007.01.027; A. Fitzpatrick et al. Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study. — American Journal of Epidemiology 165. № 1 (January 1, 2007): 14–21. https://doi.org/10.1093/aje/kwj346; R. Zee et al. Association of Shorter Mean Telomere Length with Risk of Incident Myocardial Infarction: A Prospective, Nested Case-Control Approach. — Clinica Chemica Acta 403. № 1–2, (May 2009): 139–141. https://doi.org/10.1016/j.cca.2009.02.004.
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M. McGrath et al. Telomere Length, Cigarette Smoking, and Bladder Cancer Risk in Men and Women. — Cancer Epidemiology, Biomarkers & Prevention 16. № 4 (April 2007): 815–819. https://doi.org/10.1158/1055–9965.EPI-06-0961.
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M. Sampson et al. Monocyte Telomere Shortening and Oxidative DNA Damage in Type 2 Diabetes. — Diabetes Care 29. № 2 (February 2006): 283–289. https://doi.org/10.2337/diacare.29.02.06.dc05-1715.
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A. Valdes et al. Telomere Length in Leukocytes Correlates with Bone Mineral Density and Is Shorter in Women with Osteoporosis. — Osteoporosis International 18. № 9 (September 2007): 1203–1210. https://doi.org/10.1007/s00198-007-0357-5.
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M. Shammas. Telomeres, Lifestyle, Cancer, and Aging. — Current Opinion in Clinical Nutrition and Metabolic Care 14, no.1 (January 2011): 28–34. https://doi.org/10.1097/MCO.0b013e32834121b1.
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R. Cawthon et al. Association Between Telomere Length in Blood and Mortality in People Aged 60 Years or Older. — The Lancet 361. № 9355 (February 1, 2003): 393–395. https://doi.org/10.1016/S0140-6736(03)12384-7.
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E. Epel. Accelerated Telomere Shortening in Response to Life Stress. — Proceedings of the National Academy of Science of the USA 101. № 49 (December 7, 2004): 17312–17315. https://doi.org/10.1073/pnas.040716210.
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Gr. Reynolds. Phys Ed: How Exercising Keeps Your Cells Young. — New York Times Well, January 27, 2010. https://well.blogs.nytimes.com/2010/01/27/phys-ed-how-exercising-keeps-your-cells-young/?scp=1&sq=how%20exercising%20keeps%20your%20cells%20young&st=cse.
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A. Starkweather. The Effects of Exercise on Perceived Stress and IL-6 Levels Among Older Adults. — Biological Research for Nursing 8. № 3 (January 2007): 186–194. https://www.ncbi.nlm.nih.gov/pubmed/17172317.
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V. Anisimov et al. Effect of Epitalon on Biomarkers of Aging, Life Span and Spontaneous Tumor Incidence in Female Swissderived SHR Mice. — Biogerontology 4. № 4 (2003): 193–202. https://doi.org/10.1023/A:1025114230714.
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G. Kossoy et al. Epitalon and Colon Carcinogenesis in Rats: Proliferative Activity and Apoptosis in Colon Tumors. — International Journal of Molecular Medicine 12. № 4 (October 2003): 473–475. https://doi.org/10.3892/ijmm.12.4.473.
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Br. Molgora et al. Functional Assessment of Pharmacological Telomerase Activators in Human T Cells. — Cells 2. № 1 (March 2013): 57–66. https://doi.org/10.3390/cells2010057.
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В ходе такой диеты человек временно перестает употреблять продукты, способные вызвать сильную реакцию иммунной системы и в целом нанести вред здоровью. Затем все эти продукты по очереди возвращают в рацион и наблюдают за реакцией организма. Таким образом удается выяснить, какая именно пища отрицательно воздействует на здоровье данного человека.
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Эспри Д. Меняя правила. Что помогает лидерам, новаторам и неординарным личностям побеждать. М.: Манн, Иванов и Фербер, 2021. Прим. ред.
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K. Wung Chung et al. Age-Related Sensitivity to Endotoxin-Induced Liver Inflammation: Implication of Inflammasome/IL-1β for Steatohepatitis. — Aging Cell 14. № 4 (April 2015): 526. fig. 1. https://doi.org/10.1111/acel.12305.
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A. Batchelor, J. Compston. Reduced Plasma Half-Life of Radio-Labelled 25-Hydroxyvitamin D3 in Subjects Receiving a High-Fibre Diet. — British Journal of Nutrition 49. № 2 (March 1983): 213–216. https://doi.org/10.1079/BJN19830027.
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S. Thongprakaisang et al. Glyphosate Induces Human Breast Cancer Cells Growth via Estrogen Receptors. — Food and Chemical Toxicology 59 (September 2013): 129–136. https://doi.org/10.1016/j.fct.2013.05.057.
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Fr. Peixoto. Comparative Effects of the Roundup and Glyphosate on Mitochondrial Oxidative Phosphorylation. — Chemosphere 61. № 8 (December 2005): 1115–1122. https://doi.org/10.1016/j.chemosphere.2005.03.044.
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A. Samsel, St. Seneff. Glyphosate, Pathways to Modern Diseases IV: Cancer and Related Pathologies. — Journal of Biological Physics and Chemistry 15 (2015): 121–159. https://doi.org/10.4024/11SA15R.jbpc.15.03.
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Прекурсор — исходное вещество, которое используется как один из компонентов для проведения химической реакции и получения целевого вещества.
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St. Seneff, L. Orlando. Glyphosate Substitution for Glycine During Protein Synthesis as a Causal Factor in Mesoamerican Nephropathy. — Journal of Environmental & Analytical Toxicology 8. № 1 (2018): 541. https://doi.org/10.4172/2161–0525.1000541.
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J. O’Keefe, N. Gheewala, J. O’Keefe. Dietary Strategies for Improving Post-Prandial Glucose, Lipids, Inflammation, and Cardiovascular Health. — Journal of the American College of Cardiology 51. № 3 (January 22, 2008): 249–255. https://doi.org/10.1016/j.jacc.2007.10.016.
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Кэмпбелл Т., Кэмпбелл К. Китайское исследование. Результаты самого масштабного исследования связи питания и здоровья. М.: Манн, Иванов и Фербер, 2013. Прим. ред.
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B. Altınterim. Anti-Thеroid Effects of PUFAs (Polyunsaturated Fats) and Herbs. — Trakya University Journal of Natural Sciences 13. № 2 (2012): 87–94. https://www.researchgate.net/publication/268515453_antithroid_effects_of_pufas_polyunsaturated_fats_and_herbs.
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«Зона Златовласки» — оптимальная зона для жизни, которая зависит от яркости звезды. Название взято из сказки «Три медведя», где Златовласка выбирает между холодной и горячей кашей, а берет теплую.
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M. Levine et al. Low Protein Intake Is Associated with a Major Reduction in IGF-1. Cancer, and Overall Mortality in the 65 and Younger but Not Older Population. — Cell Metabolism 19. № 3 (March 4, 2014): 407–417. https://doi.org/10.1016/j.cmet.2014.02.006.
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В 100 г говядины содержится примерно 2,6 г коллагена, в мясе птицы — 2,4 г. Прим. ред.
103
Okinawa Institute of Science and Technology (OIST) Graduate University. Fasting Ramps Up Human Metabolism. — Study Shows. ScienceDaily, January 31, 2019. https://www.sciencedaily.com/releases/2019/01/190131113934.htm.
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M. Alirezaei et al. Short-Term Fasting Induces Profound Neuronal Autophagy. — Autophagy 6. № 6 (August 2010): 702–10. https://doi.org/10.4161/auto.6.6.12376.
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G. van Meer, D. Voelker, G. Feigenson, Membrane Lipids: Where They Are and How They Behave. — Nature Reviews Molecular Cell Biology 9. № 2 (February 2008): 112–124. https://doi.org/10.1038/nrm2330.
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V. Rioux. Fatty Acid Acylation of Proteins: Specific Roles for Palmitic, Myristic and Caprylic Acids. — OCL 23. № 3 (May — June 2016): D304. https://doi.org/10.1051/ocl/2015070.
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E. Parra-Ortiz et al. Effects of Oxidation on the Physicochemical Properties of Polyunsaturated Lipid Membranes. — Journal of Colloid and Interface Science 538 (March 7, 2019): 404–419. https://doi.org/10.1016/j.jcis.2018.12.007.
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N. Simonsen et al. Adipose Tissue Omega-3 and Omega-6 Fatty Acid Content and Breast Cancer in the EURAMIC Study. — American Journal of Epidemiology 147. № 4 (February 15, 1998): 342–352. https://doi.org/10.1093/oxfordjournals.aje.a009456; S. Ghosh, E. Novak, Sh. Innis. Cardiac Proinflammatory Pathways Are Altered with Different Dietary n-6 Linoleic to n-3 Alpha-Linolenic Acid Ratios in Normal, Fat-Fed Pigs. — American Journal of Physiology: Heart and Circulatory Physiology 293. № 5 (November 2007): H2919–2927. https://doi.org/10.1152/ajpheart.00324.2007; U. Nair, H. Bartsch, J. Nair. Lipid Peroxidation-Induced DNA Damage in Cancer-Prone Inflammatory Diseases: A Review of Published Adduct Types and Levels in Humans. — Free Radical Biology & Medicine 43. № 8 (October 2007): 1109–1120. https://doi.org/10.1016/j.freeradbiomed.2007.07.012; V. Chajes, Ph. Bougnoux. Omega-6/Omega-3 Polyunsaturated Fatty Acid Ratio and Cancer, in Omega 6/Omega 3 Fatty Acid Ratio: The Scientific Evidence. — World Review of Nutrition and Dietetics. vol. 92. Basel: Karger, 2003. р. 133–151; E. Sonestedt et al. Do Both Heterocyclic Amines and Omega-6 Polyunsaturated Fatty Acids Contribute to the Incidence of Breast Cancer in Postmenopausal Women of the Malmo Diet and Cancer Cohort? — International Journal of Cancer 123. № 7 (October 1. 2008): 1637–1643. https://doi.org/10.1002/ijc.23394.
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113
Инуиты — этническая общность, состоящая из коренных народов Северной Америки.
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«Фактор страха» (англ.). Согласно правилам шоу, участники выполняют задания, в каждом из которых необходимо побороть тот или иной страх. В России выходила аналогичная передача с тем же названием.
115
Whole Foods — сеть супермаркетов в США, занимающаяся продажей органических продуктов, то есть таких, в которых вредные искусственно созданные химические соединения либо не содержатся вообще, либо содержатся в минимальном количестве.
116
Среднецепочечные триглицериды (англ. Medium-chain triglycerides, МСТ) — жиры, содержащиеся в кокосовом масле. Они метаболизируются иначе, чем длинноцепочечные триглицериды (LCT), обнаруженные в большинстве других продуктов. Масло со среднецепочечными триглицеридами содержит много этих жиров и обладает многочисленными полезными свойствами. Прим. ред.
117
Charmin — компания по производству туалетной бумаги и влажных салфеток. Прим. ред.
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C. Vandenberghe et al. Tricaprylin Alone Increases Plasma Ketone Response More Than Coconut Oil or Other Medium-Chain Triglycerides: An Acute Crossover Study in Healthy Adults/ — Current Developments in Nutrition 1. № 4 (April 1, 2017): e000257. https://doi.org/10.3945/cdn.116.000257.
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Слово составлено из hungry — «голодный» и angry — «разозленный», «разгневанный».
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A. Moreira et al. Coffee Melanoidins: Structures, Mechanisms of Formation and Potential Health Impacts, — Food & Function 3. N 9 (September 2012): 903–915. https://doi.org/10.1039/c2fo30048f.
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Ph. J. Carter et al. Longitudinal Analysis of Sleep in Relation to BMI and Body Fat in Children: The FLAME Study. — BMJ 342 (May 26, 2011): d2712. https://doi.org/10.1136/bmj.d2712.
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H. Lee et al. The Effect of Body Posture on Brain Glymphatic Transport. — The Journal of Neuroscience 34. № 31 (August 5, 2015): 11034–11044. https://doi.org/10.1523/JNEUROSCI.1625-15.2015.
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R. Ramezani, P. Stacpoole. Sleep Disorders Associated with Primary Mitochondrial Diseases. — Journal of Clinical Sleep Medicine: JCSM 10. № 11 (November 15, 2014): 1233–1239. https://doi.org/10.5664/jcsm.4212.
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Герц — единица измерения частоты периодических процессов; одно колебание в секунду. Прим. ред.
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J. Benington, H. Heller. Restoration of Brain Energy Metabolism as the Function of Sleep. — Progress in Neurobiology 45. № 4 (March 1995): 347–360. https://doi.org/10.1016/0301–0082(94)00057-O.
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How Many Hours of Deep Sleep Does One Need? — New Health Advisor, https://www.newhealthadvisor.com/How-Much-Deep-Sleep-Do-You-Need.html.
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Вариабельность сердечного ритма (англ. Heart rate variability, HRV) — физиологическое явление, проявляющееся в изменении интервала между началами двух соседних сердечных циклов. Прим. ред.
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Sleep Restriction May Reduce Heart Rate Variability. — Medscape. June 15, 2007. https://www.medscape.com/viewarticle/558331.
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Транскраниальная микрополяризация (ТКМП), или микрополяризация головного мозга, — лечебное воздействие на отдельные структуры мозга очень слабым постоянным электрическим током. Метод лечения разработан в 1970-х годах учеными Ленинградского института экспериментальной медицины. Прим. ред.
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Миллисекунда (мс) — единица времени, равная одной тысячной доле секунды. Прим. ред.
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148
Junk food буквально переводится как «еда-мусор» или «мусорная еда». Имеется в виду пища, вредная для здоровья.
149
G. Tosini, I. Ferguson, K. Tsubota. Effects of Blue Light on the Circadian System and Eye Physiology. — Molecular Vision 22 (January 24, 2016): 61–72, https://www.ncbi.nlm.nih.gov/pubmed/26900325; A.-M. Chang et al. Evening Use of Light-Emitting eReaders Negatively Affects Sleep, Circadian Timing, and Next-Morning Alertness. — Proceedings of the National Academy of Sciences of the USA 112, № 4 (January 27, 2015): 1232–1237, https://doi.org/10.1073/pnas.1418490112.
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Tosini, Ferguson, Tsubota, Effects.
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Chang et al. Evening Use.
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Bright Focus Foundation. Age-Related Macular Degeneration: — Facts and Figures. last modified January 5, 2016, https://www.brightfocus.org/macular/article/age-related-macular-facts-figures.
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Автор с расстояния 610 см видит то, что человек с нормальным зрением видит с расстояния 460 см.
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E. Loane et al. Transport and Retinal Capture of Lutein and Zeaxanthin with Reference to Age-Related Macular Degeneration. — Survey of Ophthalmology 53. № 1 (January — February 2008): 68–81. https://doi.org/10.1016/j.survophthal.2007.10.008; Le Ma et al. Effect of Lutein and Zeaxanthin on Macular Pigment and Visual Function in Patients with Early Age-Related Macular Degeneration. — Ophthalmology 119. № 11 (November 2012): 2290–2297. https://doi.org/10.1016/j.ophtha.2012.06.014.
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Крепость уединения (Fortress of Solitude) — секретное убежище Супермена.
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P. Lindqvist, H. Olsson, M. Landin-Olsson. Are Active Sun Exposure Habits Related to Lowering Risk of Type 2 Diabetes Mellitus in Women, a Prospective Cohort Study? — Diabetes Research and Clinical Practice 90. № 1 (October 2010): 109–114. https://doi.org/10.1016/j.diabres.2010.06.007.
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D. Barolet, Fr. Christiaens, M. Hamblin. Infrared and Skin: Friend or Foe. — Journal of Photochemistry and Photobiology B: Biology 155 (February 2016): 78–85. https://doi.org/10.1016/j.jphotobiol.2015.12.014.
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P. Lindqvist et al. Avoidance of Sun Exposure as a Risk Factor for Major Causes of Death: A Competing Risk Analysis of the Melanoma in Southern Sweden Cohort. — Journal of Internal Medicine 280. № 4 (October 2016): 375–387. https://doi.org/10.1111/joim.12496.
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D. Main. Why Insect Populations Are Plummeting — and Why It Matters. — National Geographic. February 14, 2019. https://www.nationalgeographic.com/animals/2019/02/why-insect-populations-are-plummeting-and-why-it-matters/.
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Cl. Ferraresi, M. Hamblin, N. Parizotto. Low-Level Laser (Light) Therapy (LLLT) on Muscle Tissue: Performance, Fatigue and Repair Benefited by the Power of Light, — Photonics & Lasers in Medicine 1. № 4 (November 1, 2012): 267–286. https://doi.org/10.1515/plm-2012-0032.
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L. Gavish et al. Low Level Laser Irradiation Stimulates Mitochondrial Membrane Potential and Disperses Subnuclear Promyelocytic Leukemia Protein, — Lasers in Surgery and Medicine 35. № 5 (December 2004): 369–376. https://doi.org/10.1002/lsm.20108.
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P. Avci et al. Low-Level Laser (Light) Therapy (LLLT) in Skin: Stimulating, Healing, Restoring. — Seminars in Cutaneous Medicine and Surgery 32. no.1 (2013): 41–52. https://www.ncbi.nlm.nih.gov/pubmed/24049929.
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S.-R. Tsai et al. Low-Level Light Therapy Potentiates NPe6-Mediated Photodynamic Therapy in a Human Osteosarcoma Cell Line via Increased ATP. — Photodiagnosis and Photodynamic Therapy 12. № 1 (March 2015): 123–130. https://doi.org/10.1016/j.pdpdt.2014.10.009.
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U. Mitchell, G. Mack. Low-Level Laser Treatment with Near-Infrared Light Increases Venous Nitric Oxide Levels Acutely: A Single-Blind. Randomized Clinical Trial of Efficacy. — American Journal of Physical Medicine & Rehabilitation 92. № 2 (February 2013): 151–156. https://doi.org/10.1097/PHM.0b013e318269d70a.
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F. Hamblin, Parizotto. Low-Level Laser (Light) Therapy.
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I. Geneva. Photobiomodulation for the Treatment of Retinal Diseases: A Review. — International Journal of Ophthalmology 9. no.1 (January 2016): 145–152. https://doi.org/10.18240/ijo.2016.01.24.
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Глутатион (GSH) — пептид, состоящий из трех ключевых аминокислот, обладающий огромной способностью бороться с окислительным стрессом и нейтрализовывать свободные радикалы. Прим. ред.
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Торговую марку TrueLight создал я, поэтому в данном случае меня можно заподозрить в предвзятости. А что касается вышеупомянутых исследований, на которые я ссылался, то по их результатам судить о возможной эффективности или неэффективности устройства TrueLight Energy Square нельзя, так как в ходе этих исследований использовались совсем другие приборы. Прим. авт.
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S. Momenzadeh et al. The Intravenous Laser Blood Irradiation in Chronic Pain and Fibromyalgia. — Journal of Lasers in Medical Sciences 6. № 1 (2015): 6–9. https://doi.org/10.22037/2010.v6i1.7800.
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V. Mikhaylov. The Use of Intravenous Laser Blood Irradiation (ILBI) at 630–640 nm to Prevent Vascular Diseases and to Increase Life Expectancy. — Laser Therapy 24. № 1 (March 31, 2015): 15–26. https://doi.org/10.5978/islsm.15-OR-02.
187
«Смерть от тысячи порезов» — казнь, применявшаяся в Китае примерно до начала XX века. Заключалась в том, что осужденному отрезали небольшие части плоти.
188
Бредесен Д. Нестареющий мозг. М.: Эксмо, 2019.
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«Трон» (1982) — американский научно-фантастический фильм, главный герой которого — программист в крупной корпорации.
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Гиппокамп — ключевое звено лимбической системы головного мозга. Ее структуры участвуют в регулировании работы внутренних органов, эмоций, памяти, пространственной навигации и других когнитивных функций. Прим. ред.
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S. McGreevey. Brain Checkpoint. — Harvard Medical School News and Research. October 25, 2018. https://hms.harvard.edu/news/brain-checkpoint.
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Br. Giunta et al. Inflammaging as a Prodrome to Alzheimer’s Disease. — Journal of Neuroinflammation 5 (2008): 51. https://doi.org/10.1186/1742-2094-5-51.
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Так в англоязычных странах стали называть боковой амиотрофический склероз после того, как от этой болезни умер легендарный американский бейсболист Генри Лу Гериг (1903–1941). Тем же недугом страдал Стивен Хокинг (1942–2018).
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Дэйл Бредесен — доктор медицины, специалист в области нейродегенеративных заболеваний, преподаватель Калифорнийского университета в Сан-Диего, США. Долгое время работал ассистентом нобелевского лауреата Стенли Прузинера в лаборатории UCSF. В своей книге «Нестареющий мозг. Глобальное медицинское открытие об истинных причинах снижения умственной активности, позволяющее обрести ясность ума, хорошую память и спасти мозг от болезни Альцгеймера» он выделил 36 метаболических факторов, приводящих к снижению умственной деятельности человека, устранив которые можно быть на 100% уверенными в полноценной работе своего мозга в любой промежуток своей жизни. Прим. ред.
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